The enormous metropolis of Metropolis is torn apart by social issues. It's a world where robots have replaced humans in many areas of production and powerful state corporations rule. It's a world filled with prejudice, violence, and unrest that grows by the day.
Detective Shunsaku Ban, along with his nephew Kenichi, arrives in Metropolis to investigate Dr. Laughton, accused of organ trafficking. However, in the doctor's laboratory, the detectives find only a girl named Tima. She is a cyborg who has lost her memory. The authorities of the city are inexplicably hunting her. Kenichi wants to help her and aids her in hiding. Meanwhile, Ban is forced to search for his nephew, uncovering the city's dark secrets in the process.